Introduction . Recently, supramolecular hydrogels derived from nucleosides have attracted increasing attention in the biomedical field due to their manifold noncovalent interactions, unique properties, and excellent biocompatibility1 , 2 , 3. Since Bang et al. reported in 1910 that concentrated solutions of guanylic acid could form a gel4, significant progress in nucleoside-based hydrogels have been developed and used in various applications, including drug delivery, bios...